Cancer (TCGA) Data Analysis

TCGA: The Cancer Genome Atlas Project (2005-2017)

• From The Cancer Genome Atlas (TCGA) consortium, a large-scale collaboration initiated and supported by the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI).

• Identifying the changes in each cancer’s complete set of DNA – its genome – and understanding how such changes interact to drive the disease will lay the foundation for improving cancer prevention, early detection and treatment.

• TCGA - The Cancer Genome Atlas

• GDC (Genomic Data Commons) Data Portal

• The Cancer Genome Atlas: Creating Lasting Value beyond Its Data (Cell. Volume 173, Issue 2, p283–285, 5 April 2018)

The Pan-Cancer Atlas (2018)

Cell. Volume 173, Issue 2 April 05, 2018

"The Cancer Genome Atlas (TCGA) team now presents the Pan-Cancer Atlas, investigating different aspects of cancer biology by analyzing the data generated during the 10+ years of the TCGA project." @CellPress

• Cell-of-Origin Patterns

• Oncogenic Processes

• Signaling Pathways

Reference:

• Home - The Cancer Genome Atlas - Cancer Genome TCGA

• Cell. Volume 173, Issue 2 April 05, 2018

• 10篇《Cell》文章及封面聚焦人類偉大成就：癌症基因組圖譜TCGA！改寫教科書式突破！_五五收藏館
  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer, Cell. Volume 173, Issue 2, p291–304.e6, 5 April 2018
  • Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics)
  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

• The Cancer Genome Atlas: Creating Lasting Value beyond Its Data (Cell. Volume 173, Issue 2, p283–285, 5 April 2018)